![]() ![]() Currently, the following benzodiazepines are approved by the Korean Food and Drug Administration (KFDA) for short-term insomnia treatment (up to 4 weeks): flurazepam, triazolam, flunitrazepam, and brotizolam. ![]() ![]() Benzodiazepines are the third most prescribed insomnia treatment drugs in the US, after benzodiazepine receptor agonists (BzRAs) such as Z-class drugs and trazodone, an antidepressant. Type 3 BDZ receptors are associated with withdrawal symptoms or resistance. Type 1 BDZ receptors are related to sleep, and type 2 receptors are associated with muscle relaxation and psychomotor dysfunction and have anticonvulsive effects. SLEEP-50 is a 50-item rating scale to detect various sleep disordersīenzodiazepines act as a benzodiazepine (BDZ) receptor agonist in the gamma aminobutryric acid (GABA-A) receptor complex to promote the binding between GABA and GABA-A receptors, the most common inhibitory neurotransmitters of the central nervous system. Morningness-Eveningness Questionnaire (MEQ) is composed of 9-item rating scales to measure a person’s circadian rhythm. It includes the following: snoring and witnessed apnea, being sleepy more than three or four times a week, and the presence of hypertension. Berlin Questionnaire (BQ) is a 10-item questionnaire to identify patients with obstructive sleep apnea. The STOP-BANG questionnaire additionally includes 4 questions about body mass index, age, neck circumference, and gender. The STOP questionnaire consists of 4 questions about snoring, tired, observed, blood pressure. STOP, STOP-Bang are rating scales to screen patients with obstructive sleep apnea. Stanford Sleepiness Scale (SSS) is a 7-point Likert-type scale and has descriptors to assess daytime subjective sleepiness. Therefore, instead of selecting a single guideline, the Working Committee decided to develop the Korean clinical guideline based on the three guidelines that reflects the various opinions of different countries.Įpworth Sleepiness Scale (ESS) is used to assess self-rated average sleepiness over usual way of life in recent times (0-24 normal <10). Recommendations for CBT-I, a non-pharmacological treatment for insomnia, were given by the ACP Treatment Guideline (2016) for the overall diagnosis and treatment of insomnia by the ESRS Treatment Guidelines (2017) and for each drug based on a detailed level of evidences by the AASM Treatment Guideline (2017). ![]() It was found that each of the three guidelines had their own characteristics that complemented each other. The AGREE II tool is composed of 23 detailed evaluation items in 6 evaluation areas, and each item is rated on a 7-point Likert scale. The three selected guidelines were evaluated by four independent raters on several aspects using the Appraisal of Guidelines for Research and Evaluation (AGREE) II tool, including quality, rigor of development, content, and applicability. The AASM, ESRS, and the American College of Physicians (ACP) guidelines were considered to be most relevant. The search results were reviewed at a meeting of the working committee and advisory committee together (June 15, 2018), Guidelines were evaluated to ensure that they were appropriate for Korean sleep medicine experts, up-to-date, and issued by reputable institutions. Vincent’s Hospital, The Catholic University of Korea, Suwon, Republic of KoreaĥDepartment of Psychiatry, Chungbuk National University Hospital, Cheongju, Republic of KoreaĦDepartment of Psychiatry, Ulsan University Hospital, Ulsan, Republic of KoreaħDepartment of Psychiatry, Armed Forces Capital Hospital, Seongnam, Republic of KoreaĨDepartment of Psychiatry, Damyang Chamsarang Hospital, Damyang, Republic of KoreaĩDepartment of Psychiatry, Doeun Hospital, Jincheon, Republic of Koreaġ0Department of Psychiatry, Dream Sleep Clinic, Seoul, Republic of Koreaġ1Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Koreaġ2Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea 1Department of Psychiatry, Veteran Health Service Medical Center, Seoul, Republic of KoreaĢClearspring Psychiatric Clinic, Seoul, Republic of KoreaģDepartment of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaĤDepartment of Psychiatry, St. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |